Recombinant Cofilin Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81548-50, E-AB-81548-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Cofilin
Target Synonym: 18 kDa phosphoprotein; CFL 1; CFL; CFL1; COF1; Cofilin 1; Cofilin 1 non muscle; Cofilin; Cofilin non muscle isoform; Cofilin-1; epididymis secretory protein Li 15; HEL-S-15; non-muscle isoform; p18
Research Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB, IHC-P, IF
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R06-2C0
UNIProt ID: P23528
Background: Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility, cytokinesis, and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Phosphorylation at Ser3 can inhibit its activity, also causing translocation from the nucleus to the cytoplasm.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human Cofilin
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
Calculated MW: 19kDa
Observed MW: 19kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only