Product Description

Recombinant Cynomolgus TSLP (C-6His)

Size: 10µg

Catalogue Number: EPT093-10

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.

Description: Recombinant Cynomolgus Thymic Stromal Lymphopoietin is produced by our E. coli expression system and the target gene encoding Tyr29-Gln159 (Glu37Gln) is expressed with a 6His tag at the C-terminus.

Alternate Names: Thymic stromal lymphopoietin,Thymic stroma-derived lymphopoietin,Tslp

Purity: Greater than 95% as determined by reducing SDS-PAGE.

Biological Activity: Immobilized Anti-Human TSLP mAb (Cat#NC066) at 2μg/ml (100 μl/well) can bind Cynomolgus TSLP-His (Cat#CR62) . The ED50 of Cynomolgus TSLP-His (Cat#CR62) is 4.48 ng/ml.

Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 

Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Molecular Weight: 16.2 KDa

Observed Molecular Weight: 16 KDa, reducing conditions

Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Storage Conditions: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Delivery Condition: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Accession: XP_005557555.1

Research Use Only