Recombinant Cytochrome C Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81449-50, E-AB-81449-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Cytochrome C
Target Synonym: Cytochrome C; Somatic; CYC; Cytochrome C; THC4; HCS
Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R09-6H3
UNIProt ID: P99999
Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human Cytochrome C
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:1000-1:2000 IHC 1:50-1:100
Calculated MW: 12kDa
Observed MW: 14kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only