Recombinant Human C1QBP Protein (aa 74-282, His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033350-10, PKSH033350-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: C1QBP
Target Synonym: Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial; ASF/SF2-Associated Protein p32; Glycoprotein gC1qBP; C1qBP; Hyaluronan-Binding Protein 1; Mitochondrial Matrix Protein p32; gC1q-R Protein; p33; C1QBP; GC1QBP; HABP1; SF2P32; gC1qR
Research Areas: Microbiology; immunology
Target Species: Human
Expression Host: E.coli
Fusion Tag: C-6His
Accession: NP_001203.1
Background: Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.
Sequence: Leu74-Gln282
Purity: > 85 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 20% Glycerol, 1mM DTT, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 24.9 kDa
Observed MW: 34 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only