Recombinant Human CNDP1 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033451-10, PKSH033451-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: CNDP1
Target Synonym: Beta-Ala-His Dipeptidase; CNDP Dipeptidase 1; Carnosine Dipeptidase 1; Glutamate Carboxypeptidase-Like Protein 2; Serum Carnosinase; CNDP1; CN1; CPGL2; HsT2308
Research Areas: Signal Transduction; Cancer;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: NP_116038.4
Background: Carnosine Dipeptidase 1 (CNDP1) belongs to the M20 metalloprotease family. CNDP1 is specifically expressed in the brain; serum and adult nervous central system. It is identified as human carnosinase. CNDP1 contains trinucleotide (CTG) repeat length polymorphism in the coding region and is inhibited by the metal chelator 1; 10-o-phenantrolin. In addition; CNDP1 can hydrolyse the beta-Ala|-His dipeptide (carnosine); anserine; Xaa-|-His dipeptides and other dipeptides including homocarnosine. CNDP1 deficiency has been associated with homocarnosinosis disease.
Sequence: Pro28-His507
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 54.9 kDa
Observed MW: 68 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only