Recombinant Human Collagen α-1(III) Chain/COL3A1 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100164-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Collagen α-1 Chain; COL3A1
Target Synonym: Collagen alpha-1(III) chain; CO3A1_HUMAN; CO3A1; PⅢCP
UNIProt ID: p02461
Research Areas: Signal Transduction; Cell biology
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: p02461
Background: Collagen type III is found in most soft connective tissues, such as skin, lung, and the vascular system, often in association with type I collagen. It is a trimer of alpha 1(III) chains that are linked by interchain disulfide bonds. Defective collagen type III is a cause of Ehlers-Danlos syndrome types III and IV and arterial aneurisms (1). This recombinant mini pro-alpha 1(III) collagen consists of a triple-helical region of Gly-Xaa-Yaa repeats, a short non-helical region, and the C-terminal propeptide. The C-terminal propeptide can be removed by the procollagen C-proteinase (BMP-1).
Sequence: Asp 1222-Leu 1466
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 26.84 kDa
Observed MW: 35 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only