Recombinant Human GABRβ3(GABRB3) protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100311-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: GABRβ3
Target Synonym: Gamma-aminobutyric acid receptor subunit beta-3; GABRB3; GABA(A) receptor subunit beta-3; GABRB3
UNIProt ID: P28472
Research Areas: Neuroscience
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His & C-His
Accession: P28472
Background: γ-aminobutyric acid type A receptor β3 subunit (GABRB3) is a candidate gene for autism spectrum conditions (ASC). Alteration in the gene results in increased tactile sensitivity, or hypersensitivity.Overexpression of GABRB3 might be implicated in the pathogenesis of heroin dependence. Aberration or mutation of this gene leads to neurodevelopmental disorders, such as Angelman syndrome, Prader-Willi syndrome and schizophrenia.[1][3] GABRB3 polymorphisms results in nonsyndromic cleft lip and/or palate (NSCL/P).
Sequence: Ser 26-Tyr 245
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 24.09 kDa
Observed MW: 32 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only