Recombinant Human IL-1b
Size: 10ug
Catalogue Number: EPT039-10
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human Interleukin-1 Beta is produced by our E. coli expression system and the target gene encoding Ala117-Ser269 is expressed.
Background: IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Other Names: Interleukin-1 beta; Catabolin; IL1F2; IL1B
Accession: P01584
Molecular Weight: 17. 5 KDa
Apparent Molecular Weight: 17 KDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0. 001 ng/µg (0. 01 EU/µg) as determined by LAL test.
Biological Activity: Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells(Cat#XCC10). The ED50 for this effect is 20-100 pg/ml.
Storage: Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Delivery Conditions: The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
Research Use Only.