Recombinant Human IL2RG/CD132 Protein (Fc & His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032573-10, PKSH032573-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: IL2RG; CD132
Target Synonym: Cytokine receptor common subunit gamma; Interleukin-2 receptor subunit gamma; gammaC; P64; CD132; IL2RG; SCIDX; SCIDX1; CIDX
UNIProt ID: P31785
Research Areas: Cancer; immunology
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-Fc-6His
Accession: P31785
Background: IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors; including those of interleukin -2; -4; -7 and -21; and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).
Sequence: Leu23-Ala262
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 29.3 kDa
Observed MW: 57 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only