Recombinant Human Inhibin β C Chain/INHBC Protein (aa 19-352, His Tag)(Active)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032586-10, PKSH032586-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Inhibin β C Chain; INHBC
Target Symptom: Inhibin Beta C Chain; Activin Beta-C Chain; INHBC
Research Area: Signal Transduction; Neuroscience;
Target Species: Human
Expression Host: HEK293 Cells
Application: ELISA
Fusion Tag: C-6His
UNIProt ID: P55103
Accession: P55103
Background: Inhibin beta C chain; also known as activin beta-C chain and INHBC; belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits; linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only. Inhibins/activins regulates many physiological processes; such as hypothalamic and pituitary hormone secretion; gonadal hormone secretion; germ cell development and maturation; erythroid differentiation; insulin secretion; nerve cell survival; embryonic axial development or bone growth and so on.
Activity: Immobilized Human INHBC-His at 0.5μg/ml(100 μl/well) can bind Human ACVR2A-Fc(Cat: PKSH032039). The ED50 of Human INHBC-His is 4. 5 ug/ml.
Sequence: Thr19-Ser352
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 37.5 kDa
Observed MW: 49 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only