Recombinant Human Inhibin β C Chain/INHBC Protein (aa 237-352, His Tag)(Active)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032587-10, PKSH032587-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Inhibin β C Chain; INHBC
Target Symptom: Inhibin Beta C Chain; Activin Beta-C Chain; INHBC
Research Area: Signal Transduction; Neuroscience;
Target Species: Human
Expression Host: E.coli
Application: ELISA
Fusion Tag: N-6His
UNIProt ID: P55103
Accession: P55103
Background: Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion; gonadal hormone secretion; germ cell development and maturation; erythroid differentiation; insulin secretion; nerve cell survival; embryonic axial development or bone growth; depending on their subunit composition. Inhibins appear to oppose the functions of activins; Inhibins and activins inhibit and activate; respectively; the secretion of follitropin by the pituitary gland.
Activity: Immobilized Human INHBC-His at 0.8μg/ml(100 μl/well) can bind Human ACVR2A-Fc(Cat: PKSH032039). The ED50 of Human INHBC-His is 6. 73 ug/ml.
Sequence: Gly237-Ser352
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 4mM HCl, 1mM DTT.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 14.8 kDa
Observed MW: 16 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only