Recombinant Human Kallikrein 10/KLK10 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032665-10, PKSH032665-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Kallikrein 10; KLK10
Target Synonym: Kallikrein-10; Normal Epithelial Cell-Specific 1; Protease Serine-Like 1; KLK10; NES1; PRSSL1
UNIProt ID: O43240
Research Areas: Signal Transduction; Cell biology; Cancer;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: O43240
Background: Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Sequence: Ala31-Asn276
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 28.0 kDa
Observed MW: 34 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only