Recombinant Human Kallikrein 4/KLK4 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032667-10, PKSH032667-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Kallikrein 4; KLK4
Target Synonym: Kallikrein-4; Enamel Matrix Serine Proteinase 1; Kallikrein-Like Protein 1; KLK-L1; Prostase; Serine Protease 17; KLK4; EMSP1; PRSS17; PSTS; AI2A1; ARM1; EMSP; kallikrein; KLK-L1
UNIProt ID: Q9Y5K2
Research Areas: Signal Transduction; Cell biology; Cancer;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q9Y5K2
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Sequence: Ser27-Ser254
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 25.4 kDa
Observed MW: 30 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only