Product Description

Recombinant Human NPR3 (C-Fc)

Size: 50µg

Catalogue Number: EPT167-50

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Atrial Natriuretic Peptide Receptor-3 (NPR3) , also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Osteocrin was found to be a specific ligand to NPR3. NPR3 is necessary for Osteocrin to regulate femoral, tibial, and metatarsal bone elongation.

Description: Recombinant Human Atrial Natriuretic Peptide Receptor 3 is produced by our Mammalian expression system and the target gene encoding Thr24-Glu481 is expressed with a Fc tag at the C-terminus.

Alternate Names: ANP-C, ANPR-C, NPR3, NPRC, NPR-C,ANPRC, C5orf23

Purity: Greater than 95% as determined by reducing SDS-PAGE.

Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 

Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Molecular Weight: 77.5 KDa

Observed Molecular Weight: 90-100 KDa, reducing conditions

Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Storage Conditions: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Delivery Condition: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Accession: P17342

Research Use Only