Recombinant Human PP2A-Cα/PPP2CA protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100357-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: PP2A-Cα; PPP2CA
Target Synonym: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PPP2CA;
PP2A-alpha; Replication protein C (RP-C); PPP2CA
UNIProt ID: P67775
Research Areas: Cancer; Signal Transduction;
Cell Biology
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His & C-His
Accession: P67775
Background: Protein Phosphatase 2A (PP2A) is an enzyme that removes phosphates covalently attached to serine and threonine residues in proteins. It contains three subunits; a catalytic subunit C (PP2Ac), an assembly/structural subunit A (PP2Aa), and a regulatory subunit B (PP2Ab). PP2A is a ubiquitous enzyme that plays a role in regulating many cellular activities varying from ion transport in erythrocytes to suppressing tumor growth. Binding of the SV40 small T antigen to the PP2A phosphatase complex is known to cause oncogenic transformation.
Sequence: Met 1-Leu 309
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 39.3 kDa
Observed MW: 40 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only