Recombinant ILF3 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81475-50, E-AB-81475-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: ILF3
Target Synonym: CBTF; Double stranded RNA binding protein 76; Double-stranded RNA-binding protein 76; DRBF; DRBP76; ILF3; ILF3; Interleukin enhancer binding factor 3; Interleukin enhancer-binding factor 3; M phase phosphoprotein 4; M-phase phosphoprotein 4; MPHOSPH4; MPP4; NF AT 90; NF-AT-90; NF110; NF90; NFAR; Nuclear factor associated with dsRNA; Nuclear factor of activated T cells 90 kDa; Nuclear factor of activated T-cells 90 kDa; TCP80; Translational control protein 80
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB, IHC-P, IF
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R04-3C1
UNIProt ID: Q12906
Background: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human ILF3
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:2000-1:5000 IHC 1:50-1:100 IF 1:50-1:100
Calculated MW: 95kDa
Observed MW: 95kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only