Recombinant Mouse NTPDase 2/ENTPD2 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSM041340-10, PKSM041340-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: NTPDase 2; ENTPD2
Target Synonym: Ectonucleoside triphosphate diphosphohydrolase 2; Entpd2; Ecto-Nucleoside Triphosphate Diphosphohydrolase 2
UNIProt ID: O55026
Target Species: Mouse
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: O55026
Background: CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by preferentially converting ATP to ADP. CD39L1 plays a role in regulating thrombosis and inflammation which is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation. Alternative splicing of CD39L1 gene results in multiple transcript variants.
Sequence: Cys26-Ser462
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris, 10mM CaCl2, 150mMNaCl, 10%Glycerol, pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 49.2 kDa
Observed MW: 63-90 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only