Recombinant PERK Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81482-50, E-AB-81482-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: PERK
Target Synonym: DKFZp781H1925; E2AK3; EC 2.7.11.1; Eif2ak3; Eukaryotic translation initiation factor 2 alpha kinase 3; Eukaryotic translation initiation factor 2-alpha kinase 3; Heme regulated EIF2 alpha kinase; HRI; HsPEK; Pancreatic eIF2 alpha kinase; Pancreatic eIF2-alpha kinase; PEK; PRKR like endoplasmic reticulum kinase; PRKR-like endoplasmic reticulum kinase; WRS
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R09-1F9
UNIProt ID: Q9NZJ5
Background: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Concentration: 300 μg/mL
Immunogen: Recombinant protein of human PERK
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000
Calculated MW: 125kDa
Observed MW: 140kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only