Recombinant PRMT7 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81600-50, E-AB-81600-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: PRMT7
Target Synonym: [Myelin basic protein]-arginine N-methyltransferase PRMT7; ANM7; FLJ10640; Histone-arginine N-methyltransferase PRMT7; KIAA1933; Myelin basic protein arginine N methyltransferase; OTTHUMP00000174863; PRMT7; Protein arginine methyltransferase 7; Protein arginine N-methyltransferase 7
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R06-4F6
UNIProt ID: Q9NVM4
Background: Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human PRMT7
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:2000
Calculated MW: 79kDa
Observed MW: 79kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only