Recombinant Rabbit TNF-α protein (His tag)
Size: 100μg
Catalogue Numbers: PDEO100005-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: TNF-α
Target Synonym: Tumor Necrosis Factor; Cachectin; TNF-Alpha; TNF-a; TNF; TNFA; TNFSF2
UNIProt ID: P04924
Research Areas: Immunology; Signal Transduction; Microbiology; Cancer; Cardiovascular
Target Species: Rabbit
Expression Host: E.coli
Fusion Tag: N-His
Accession: P04924
Background: Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1, p55R) and TNF-R2 (TNF receptor type 2, p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
Sequence: Leu 80-Leu 235
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 17.05 kDa
Observed MW: 18 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only