Recombinant Rad21 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81508-50, E-AB-81508-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Rad21
Target Synonym: MGS; HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Hamster
Application: WB, IHC-P
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R03-5I0
UNIProt ID: O60216
Background: RAD21, also named as Nuclear matrix protein 1, is a 631 amino acid protein, which belongs to the rad21 family. The calculated molecular weight of RAD21 is 72 kDa, but the phosphorylated RAD21 is about 120 kDa. The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human Rad21
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:50-1:100
Calculated MW: 72kDa
Observed MW: 130kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only