Recombinant TGF beta 1 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81441-50, E-AB-81441-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: TGF beta 1
Target Synonym: TGF beta 1; TGFB; CED; LAP
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R08-8B7
UNIProt ID: P04202
Background: TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).
Concentration: 300 μg/mL
Immunogen: Recombinant protein of mouse TGF beta 1
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000
Calculated MW: 44kDa
Observed MW: 44kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only