Recombinant YTHDF1 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81517-50, E-AB-81517-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: YTHDF1
Target Synonym: C20orf21; DF1
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Hamster
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R05-2E7
UNIProt ID: P59326
Background: YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.
Concentration: 300 μg/mL
Immunogen: Recombinant protein of human YTHDF1
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:1000-1:2000
Calculated MW: 61kDa
Observed MW: 61kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only