Product Description

Resistin Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES13423-50, ES13423-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: IHC, ELISA

Alternate Names: Resistin (Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human Resistin AA range: 1-50

Isotype: IgG

Target: Resistin

Specificity: This antibody detects endogenous levels of human Resistin

Dilution: IHC-p 1:50-200, ELISA(peptide)1:5000-20000

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in white adipose tissue (at protein level) (PubMed:11201732), Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood (PubMed:15248836), Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues (PubMed:15064728), Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus (PubMed:15248836),

Function: Function: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes
Similarity: Belongs to the resistin/FIZZ family
Subunit: Homodimer, disulfide-linked
Tissue Specificity: Expressed only in fatty tissues

Subcellular Location: Secreted

Storage and Stability: -20°C/1 year

Gene Name: RETN FIZZ3 HXCP1 RSTN UNQ407/PRO1199

Protein Name: Resistin

Research Use Only