Product Description

RFX4 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES13410-50, ES13410-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human RFX4 AA range: 439-489

Isotype: IgG

Target: RFX4

Specificity: This antibody detects endogenous levels of RFX4 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Isoform 1: Expressed in brain and gliomas (at protein level), Isoform 2: Testis-specific (at protein level), Isoform 3: Testis-specific (at protein level), Isoform 3: Expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes, Isoform 4: Testis-specific,

Molecular Weight (Da): 81kD

Function: Function: May activate transcription by interacting directly with the X-box
Similarity: Belongs to the RFX family
Subunit: Homodimer. Heterodimer with RFX2 and RFX3. Binds DNA
Tissue Specificity: Isoform 4 is testis-specific. Isoform 1 is expressed in brain and gliomas. Isoform 2 and isoform 3 are testis-specific (at protein level). Isoform 1 is expressed in brain (at protein level). Isoform 3 is expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: RFX4

Protein Name: RFX4

Mouse Gene ID: 71137

Mouse SwissProt Number: Q7TNK1

Research Use Only