Rig-I/DDX58 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0550-20, A0550-100
Citations, Manuals and MSDS Available upon request.
Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 107kDa
Observed Molecular Weight: 107kDa/
Immunogen: Synthetic peptide
Species: Human
GeneID: 23586
SWISS: O95786
Alternate Names: RIG1; DDX58; RIG-I; RLR-1; SGMRT2; Rig-I/DDX58
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:2000 - 1:4000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Immunology Inflammation, Toll-like Receptor Signaling Pathway.
NCBI Alias: RIGI
Research Use Only