Product Description

ROA0 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES8993-50, ES8993-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein. at AA range: 20-100

Isotype: IgG

Target: ROA0

Specificity: ROA0 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Brain, Colon carcinoma, Eye, Lung, Muscle, Ovarian carcinoma, Pla

Observed Band (KD): 33kD

Function: Function: This protein is a component of ribonucleosomes
PTM: Arg-291 is dimethylated, probably to asymmetric dimethylarginine
Similarity: Contains 2 RRM (RNA recognition motif) domains
Subcellular Location: Component of ribonucleosomes

Subcellular Location: Nucleus Component of ribonucleosomes

Storage and Stability: -20°C/1 year

Gene Name: HNRNPA0 HNRPA0

Protein Name: Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)

Mouse SwissProt Number: Q9CX86

Research Use Only