RPGF2 Polyclonal Antibody - BT-AP13914

RPGF2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13914-20, BT-AP13914-50, BT-AP13914-100

Citations, Manuals and MSDS Available upon request.

Background: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000

Research Areas: Neuroscience; Signal transduction

Target Protein: RAPGEF2

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Rap guanine nucleotide exchange factor 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y4G8; Mouse: Q8CHG7; Rat: F1M386

Synonyms: Rap guanine nucleotide exchange factor 2;Neural RAP guanine nucleotide exchange protein;nRap GEP;PDZ domain-containing guanine nucleotide exchange factor 1;PDZ-GEF1;RA-GEF

GeneID: Human: 9693

Research Use Only