Product Description

RSPO1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-67973-60, E-AB-67973-120, E-AB-67973-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: RSPO1

Target Synonym: RSPO1; CRISTIN3; RSPO

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q2MKA7

Background: This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human RSPO1 (NP_001033722.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only