RSPO3 Polyclonal Antibody - BT-AP13952

RSPO3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13952-20, BT-AP13952-50, BT-AP13952-100

Citations, Manuals and MSDS Available upon request.

Background: This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development.

Research Areas: Developmental biology; Stem cells

Target Protein: RSPO3

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: R-spondin-3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9BXY4; Mouse: Q2TJ95

Synonyms: R-spondin-3;Protein with TSP type-1 repeat;hPWTSR;Roof plate-specific spondin-3;hRspo3;Thrombospondin type-1 domain-containing protein 2

GeneID: Human: 84870

Research Use Only