Product Description

RXRA Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13978-20, BT-AP13978-50, BT-AP13978-100

Citations, Manuals and MSDS Available upon request.

Background: Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.

Research Areas: Cancer; Epigenetics and nuclear signaling; Metabolism; Signal transduction

Target Protein: RXRA

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Retinoic acid receptor RXR-alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P19793; Mouse: P28700; Rat: Q05343

Synonyms: Retinoic acid receptor RXR-alpha;Nuclear receptor subfamily 2 group B member 1;Retinoid X receptor alpha

GeneID: Human: 6256

Research Use Only