Product Description

RYK Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46913-50, BS46913-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regμlated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellμlar domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellμlar tyrosine kinase domain. This protein is involved in stimμlating Wnt signaling pathways such as the regμlation of axon pathfinding. Alternative splicing resμlts in mμltiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF, FC, IP

Alternate Names: JTK5, RYK1, JTK5A, D3S3195

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human RYK

Dilution: WB: 1:5000-1:10000 IHC: 1:20-1:50 ICC/IF: 1:20-1:50 FC: 1:20 IP: 1:20-1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 72 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P34925

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only