Product Description

SμlT2A1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7253-50, BS7253-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: SμlT1 sμlfotransferases exhibit N-sμlfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SμlT2 enzymes prefer hydroxysteroids and SμlT3 family members are selective for N-substituted aryl and alicyclic compounds. SμlT2A1 catalyzes the sμlfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SμlT2A1 plays a role in hepatic cholesterol homeostasis. SμlT2B1 consists of two isoforms, SμlT2B1a and SμlT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sμlphation of 3b-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SμlT2B1b is expressed in prostate, skin, placenta and lung.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Bile salt sμlfotransferase, Dehydroepiandrosterone sμlfotransferase, DHEA-ST, Hydroxysteroid Sμlfotransferase, HST, ST2, ST2A3, Sμlfotransferase 2A1, ST2A1, HST, STD

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human SμlT2A1 .

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SμlT2A1 polyclonal antibody detects endogenous levels of SμlT2A1 protein.

Molecular Weight: ~ 36 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q06520

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only