Product Description

SAPAP1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3407-50, ES3407-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: DLGAP1, DAP1, GKAP, Disks large-associated protein 1, DAP-1, Guanylate kinase-associated protein, hGKAP, PSD-95/SAP90-binding protein 1, SAP90/PSD-95-associated protein 1, SAPAP1

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human DLGP1. AA range:791-840

Isotype: IgG

Target: SAPAP1

Specificity: SAPAP1 Polyclonal Antibody detects endogenous levels of SAPAP1 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in brain,

Observed Band (KD): 108kD

Fields: Glutamatergic synapse

Function: Function: Part of the postsynaptic scaffold in neuronal cells
Similarity: Belongs to the SAPAP family
Subcellular Location: Found in postsynaptic density of neuronal cells
Subunit: Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1
Tissue Specificity: Expressed in brain

Subcellular Location: Cell membrane, Peripheral membrane protein Cell junction, synapse, postsynaptic density Cell junction, synapse

Storage and Stability: -20°C/1 year

Gene Name: DLGAP1

Protein Name: Disks large-associated protein 1

Mouse Gene ID: 224997

Mouse SwissProt Number: Q9D415

Rat Gene ID: 65040

Rat SwissProt Number: P97836

Research Use Only