SARS-CoV-2 E Protein Polyclonal Antibody (2019-nCoV)
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-V1033-50, E-AB-V1033-100
Citations, Manuals and MSDS Available upon request.
Target Synonym: 2019-nCoV E protein; 2019-nCoV sM protein; Envelope small membrane protein
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: SARS-COV2
Application: ELISA
Isotype: IgG
Clonality: Polyclonal
Background: Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Concentration: 0.30mg/ml
Immunogen: Recombinant SARS-CoV-2 E protein
Buffer: PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Dilution: ELISA:1:4000~1:8000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only