SCN8A Polyclonal Antibody - BT-AP14078

SCN8A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14078-20, BT-AP14078-50, BT-AP14078-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.

Research Areas: Neuroscience

Target Protein: SCN8A

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Sodium channel protein type 8 subunit alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9UQD0; Mouse: Q9WTU3; Rat: O88420

Synonyms: Sodium channel protein type 8 subunit alpha;Sodium channel protein type VIII subunit alpha;Voltage-gated sodium channel subunit alpha Nav1.6

GeneID: Human: 6334

Research Use Only