Product Description

SCNBA Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34761-50, RA34761-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: sodium voltage-gated channel alpha subunit 11 (SCN11A) Homo sapiens Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM, Apr 2004],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 197

Protein Molecular Weight (kDa): 197

Storage: -20°C/1 year

Human Gene ID: 11280

Human SwissProt Number: Q9UI33

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only