Product Description

SENP3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29724-50, RA29724-100

Citations, Manuals and MSDS Available upon request.

Background: SUMO1/sentrin/SMT3 specific peptidase 3 (SENP3) Homo sapiens The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]) .[supplied by OMIM, Jun 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: SENP3; SSP3; SUSP3; Sentrin-specific protease 3; SUMO-1-specific protease 3; Sentrin/SUMO-specific protease SENP3

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 26168

Protein MW (KDa): 80

SWISS: Q9H4L4

Source: Rabbit

Research Use Only