Product Description

SETBP Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES13145-50, ES13145-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human SETBP AA range: 990-1040

Isotype: IgG

Target: SETBP

Specificity: This antibody detects endogenous levels of SETBP at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in numerous tissues, Expressed at low levels in myeloid and monocytic cells as well as in CD34+ cells, expression levels are higher in myeloid malignancies,

Molecular Weight (Da): 176kD

Function: Similarity: Contains 3 A.T hook DNA-binding domains
Subunit: Interacts with SET
Tissue Specificity: Expressed in numerous tissues

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: SETBP1 KIAA0437

Protein Name: SETBP

Mouse Gene ID: 240427

Mouse SwissProt Number: Q9Z180

Research Use Only