SGMR1 Polyclonal Antibody - BT-AP14170

SGMR1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14170-20, BT-AP14170-50, BT-AP14170-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

Research Areas: Cancer; Cardiovascular; Neuroscience; Signal transduction

Target Protein: SIGMAR1

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Sigma non-opioid intracellular receptor 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q99720; Mouse: O55242; Rat: Q9R0C9

Synonyms: Sigma non-opioid intracellular receptor 1;Aging-associated gene 8 protein;SR31747-binding protein;SR-BP;Sigma 1-type opioid receptor;SIG-1R;Sigma1-receptor;Sigma1R;hSigmaR1

GeneID: Human: 10280

Research Use Only