SH3G3 Polyclonal Antibody - BT-AP14189

SH3G3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14189-20, BT-AP14189-50, BT-AP14189-100

Citations, Manuals and MSDS Available upon request.

Background: An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.,Implicated in endocytosis. May recruit other proteins to membranes with high curvature.,Belongs to the endophilin family.,Contains 1 BAR domain.,Contains 1 SH3 domain.,subcellular location:Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons.,subunit:Interacts with ARC (By similarity). Interacts with DNM1, SGIP1 and SYNJ1. Interacts with the huntingtin exon 1 protein (HDEX1P) containing a glutamine repeat in the pathological range and promotes formation of insoluble polyglutamine-containing aggregates in vivo.,tissue specificity:Brain and testis.,

Research Areas: Neuroscience; Signal transduction

Target Protein: SH3GL3

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Endophilin-A3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q99963; Mouse: Q62421; Rat: O35180

Synonyms: Endophilin-A3;EEN-B2;Endophilin-3;SH3 domain protein 2C;SH3 domain-containing GRB2-like protein 3

GeneID: Human: 6457

Research Use Only