Product Description

SIK1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34860-50, RA34860-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., enzyme regulation:Activated by phosphorylation on Thr-182 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39., function:Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 UBA domain., subcellular location:Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ., subunit:Binds to and is activated by YWHAZ when phosphorylated on Thr-182.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 86

Protein Molecular Weight (kDa): 86

Storage: -20°C/1 year

Human Gene ID: 150094

Human SwissProt Number: P57059

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only