SOX-2 Monoclonal Antibody - PA7179

SOX-2 Monoclonal Antibody

Sizes: 100μL, 200μL

Catalogue Numbers: PA7179-100, PA7179-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SOX-2

Target Synonym: ANOP3, cb236, Delta EF2a, lcc, MCOPS3, MGC148683, MGC2413, RGD1565646, Sex determining region Y box 2, SOX 2, Sox2, SOX2, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, SRY-box 2, Transcription factor SOX 2, Transcription factor SOX-2, ysb

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC-P

Clonality: Monoclonal

Clone No.: YN02195r

UNIProt ID: P48431

Background: The SOX2 gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors, which plays an important role in early organ development. SOX2 can be used in the auxiliary diagnosis of germ cell tumors. 90% of embryonic cancers express SOX2, but not in seminoma, yolk sac tumor and choriocarcinoma. SOX2 has been shown to be a negative prognostic factor and associated with aggressive phenotypes in breast, head and neck, gastric, colorectal and bladder cancers. In small cell lung cancers, SOX2 was also correlated with a poor prognosis. Conversely, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and was shown to be an independent positive prognostic marker.

The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.

Shipping: Ice bag

Research Use Only