SOX2 Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A19118PM-20, A19118PM-100
Citations, Manuals and MSDS Available upon request.
Background: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) .
Category: Monoclonal Antibodies
Applications: WB, IP, IF/ICC, IF-P, IHC-P, ChIP, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 34 kDa
Observed Molecular Weight: 35 kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 6657
SWISS: P48431
Alternate Names: ANOP3; MCOPS3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:3000 - 1:15000 IP, 0.5μg-4μg antibody for 500μg-700μg extracts of whole cells IF/ICC, 1:50 - 1:200 IF-P, 1:50 - 1:200 IHC-P, 1:200 - 1:800 ChIP, 3μg antibody for 10μg-15μg of Chromatin ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Signal Transduction, Cell Biology Developmental Biology, ESC Pluripotency and Differentiation, Neuroscience, Cell Type Marker, Stem Cells, Embryonic Stem Cells, Germline Stem Cells.
NCBI Alias: SOX2
Research Use Only