SP1 Polyclonal Antibody - E-AB-16069

SP1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16069-60, E-AB-16069-120, E-AB-16069-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SP1

Target Synonym: SP 1; SP1; Sp1 transcription factor; SP1; Specificity protein 1; Transcription factor Sp1; TSFP 1; TSFP1

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P08047

Background: The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.2 mg/mL

Immunogen: Synthetic peptide of human SP1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only