SP100 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-61150-60, E-AB-61150-120, E-AB-61150-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SP100
Target Synonym: SP100; lysp100b
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Tags and Cell Markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P23497
Background: This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human SP100 (NP_001193631.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 50kDa/53kDa/78kDa/100kDa/101kDa
Observed MW: 66-100kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only