SP140 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A17634-20, A17634-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 98kDa
Observed Molecular Weight: 98kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 11262
SWISS: Q13342
Alternate Names: LYSP100; LYSP100-A; LYSP100-B; SP140
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Immunology Inflammation.
NCBI Alias: SP140
Research Use Only