Product Description

SPAG8 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34973-50, RA34973-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: sperm associated antigen 8 (SPAG8) Homo sapiens The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Al

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 46

Protein Molecular Weight (kDa): 46

Storage: -20°C/1 year

Human Gene ID: 26206

Human SwissProt Number: Q99932

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only