SPCS2 Polyclonal Antibody - E-AB-18383

SPCS2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18383-60, E-AB-18383-120, E-AB-18383-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SPCS2

Target Synonym: Microsomal signal peptidase 25 kDa subunit; Signal peptidase complex subunit 2; Signal peptidase complex subunit 2 homolog (S. cerevisiae); SPase 25 kDa subunit; SPCS2; SPCS2

Research Areas: Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q15005

Background: SPCS2 (signal peptidase complex subunit 2), also known as SPC25 or microsomal signal peptidase 25 kDa subunit, is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1, 400 genes and comprises nearly 4% of the human genome.

Concentration: 1.1 mg/mL

Immunogen: Fusion protein of human SPCS2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Calculated MW: 25 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only