SPDYA Polyclonal Antibody - E-AB-64746

SPDYA Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-64746-60, E-AB-64746-120, E-AB-64746-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SPDYA

Target Synonym: SPDYA; RINGO3; RINGOA; SPDY1; SPY1

Research Areas: Cell Biology,Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q5MJ70

Background: Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Mediates cell survival during the DNA damage process through activation of CDK2.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human SPDYA

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 33kDa/36kDa

Observed MW: 50kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only